Doctoral Candidates
ProgRET will give Doctoral Candidates (DCs) unparalleled training opportunities in outstanding academic and industrial settings through training-by-research via individual research projects, secondments, and network-wide training sessions. All individual training and research activities will provide each DC with the necessary skills in academic and industrial research.
The PhD candidates will obtain PhD diplomas from reputed universities within the ProgRET project.
The PhD candidates will obtain PhD diplomas from reputed universities within the ProgRET project.
WP1 – UNDERSTANDING MECHANISMS UNDERLYING adIRD IN RETINAL STEM-CELL DERIVED AND ANIMAL MODELS
DC1
Sofia Manzo
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Impact of ageing on 3D genome architecture in adIRD model in killifish, an aquatic animal model
Supervisor: Prof. JR Martinez-Morales
Host institute: The Andalusian Centre of Developmental Biology, Spain Secondments: Evotec, Germany; Ghent University, Belgium Doctoral program: Biotechnology at the Pablo de Olavide University |
Characterization of stem cell models for defective spliceosome components in adIRD
Supervisor: Prof. D. Staněk
Host institute: Institute of Molecular Genetics, Czech Republic Secondments: Evotec, Germany; Institute for Neurosciences of Montpellier, France Doctoral program: Developmental and Cell Biology at Charles University Prague |
DC2
Carolina Silva
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DC3
Lihan Xu
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High throughput screening assay for dominant BEST1 mutations to identify
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WP2 – ADVANCING DIAGNOSTICS IN adIRD USING A SINGLE-MOLECULE MULTI-OMICS FRAMEWORK
Definition of transcriptional units of adIRD genes in human retina, RPE, PPCs and
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DC4
Samuel Santamaria
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DC5
Nelson Martins
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Mapping of 3D genome topologies in human retina, RPE, PPCs and ROs
Supervisor: Prof. E. De Baere
Host institute: Ghent University, Belgium Secondments: Phenopolis, UK (virtual); The Andalusian Centre of Developmental Biology, Spain; The Institute of Molecular and Clinical Ophthalmology Basel, Switzerland Doctoral program: Medicine and Health Sciences at Ghent University |
Single-molecule multi-omics framework for adIRD diagnosis
Supervisor: Dr. S. Roosing
Host institute: Radboud University Medical Center Nijmegen, The Netherlands Secondments: Phenopolis, UK (virtual); The Institute of Molecular and Clinical Ophthalmology Basel, Switzerland; Ghent University, Belgium Doctoral program: Donders Institute for Brain, Cognition and Behavior at Radboud University Nijmegen |
DC6
Stefanida Shliaga
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WP3 – THERAPEUTIC STRATEGIES FOR adIRD USING RNA THERAPY AND GENOME EDITING
DC7
Hossein Dehghan Banadaki
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Allele-specific invalidation of dominant-negative mutations in PRPH2
Supervisor: Prof. R. Collin
Host institute: Radboud University Medical Center Nijmegen, The Netherlands Secondments: Ghent University, Belgium; Gulliver Biomed, Belgium Doctoral program: Donders Institute for Brain, Cognition and Behavior at Radboud University Nijmegen |
Allele-independent increase of protein translation for adIRD genes displaying haplo-insufficiency
Supervisor: Prof. F. Coppieters
Host institute: Ghent University, Belgium Secondments: Evotec, Germany; Radboud University Medical Center Nijmegen, The Netherlands Doctoral program: Medicine and Health Sciences at Ghent University |
DC8
Álvaro González Cid
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DC9
Maddalena Fuso
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Allele-specific, mutation-independent rescue of dominant negative acting IRD
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Evaluating allele-specific invalidation therapies for autosomal dominant CRX
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DC10
Kobe Outtier
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