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Fishy Business

3/8/2026

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What can a tiny fish teach us about the secrets of human aging?
Meet the Killifish; the shortest-lived vertebrate that can be raised in a lab. With a lifespan of just 4 to 6 months, it’s a "fast-forward" model for understanding how our eyes age and why retinal dystrophies occur.
In our latest video, Sofia Manzo (DC1) dives into her research on 3D genome architecture and how "switching" genes on and off over time affects our vision.
By studying the epigenetics of this remarkable fish, the PROGRET network is working toward new strategies to preserve vision and combat retina degeneration.
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HORIZON-MSCA-2022-DN — ProgRET  — No.101120562
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